Surviving the Interim: Insights Into Interim Survival Analysis
نویسنده
چکیده
Pre-specified interim analyses may be performed to evaluate whether a clinical trial can be halted prematurely for overwhelming efficacy and/or futility. This approach is somewhat more complex when the primary endpoint is a survival analysis. This paper provides an overview of performing the initial calculations and actual interim analyses using SAS ® PROC SEQDESIGN and PROC SEQTEST, EAST ® software, and PASS ® software.
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